In addition to getting into mischief around his neighborhood, Dennis often finds himself in competition with a local bully named Joey and has to outsmart him in order to come out on top. Mr. Wilson, Dennis's grumpy next-door neighbor, is a constant source of frustration for Dennis as he always seems to get caught up in Dennis's antics.
Throughout the series, Dennis and his friends get into all sorts of adventures, from trying to catch a mysterious creature in the woods to participating in a pet show with Ruff. Despite his mischievous nature, Dennis always means well and is ultimately a good-hearted and loyal friend.
Overall, the show highlights the misadventures of Dennis the Menace and the antics he gets up to with his friends, all while navigating the challenges of growing up and learning important life lessons along the way.