Vampirus is a horror-comedy movie that centers around a young vampire named Ava, who is struggling to find her next meal during the coronavirus quarantine. With humans staying indoors and practicing social distancing, Ava finds it challenging to hunt for blood and survive.
Desperate for sustenance, Ava teams up with an unlikely ally, a human named Max. Max is a comic book nerd with a wild imagination who has been spending the lockdown period creating his own superheroes. They team up to hunt down prey and satisfy Ava's bloodlust. Max helps Ava blend in with the human world, giving her tips on how to behave like a human, including wearing a mask to conceal her fangs, avoiding sunlight, and adapting her feeding habits.
The duo's partnership soon proves successful, and they begin to develop a strong bond, with Ava seeing a different side to humanity through Max's friendship. However, their partnership is threatened when Max's sister discovers Ava's true identity and becomes determined to expose her to the world.
As they navigate the twists and turns of their unconventional relationship, Ava and Max must confront their differences and overcome their unique challenges to remain allies and survive the uncertainties of the quarantine life. The movie ends on an exciting note as they face the biggest challenge of their partnership yet, and their bond is put to the ultimate test.