In The Muppets Take Manhattan, Kermit and his friends create a musical called "Manhattan Melodies," which they hope will become a hit on Broadway. However, they struggle to find a producer who will give them a chance, due to their lack of experience and unconventional cast.
In their search for a producer, the Muppets encounter a variety of challenges and mishaps, including getting lost in the city, accidentally joining a group of rats in a diner, and even getting their identities stolen by a group of impostors.
Despite these setbacks, the Muppets never lose their determination and continue to rehearse and improve their show. They eventually catch the attention of a producer named Bernard Crawford, who agrees to stage their musical.
As the Muppets prepare for their big Broadway debut, Miss Piggy is offered a job as a fashion model and decides to leave the group. However, when she sees how much the others depend on her and how important their show is to them, she returns to the Muppets and delivers a stunning performance in the musical's finale.
In the end, "Manhattan Melodies" becomes a huge success, and the Muppets are one step closer to achieving their dreams of becoming famous performers. The movie ends with the Muppets graduating from Danhurst College once again, but this time as successful Broadway stars.