The Domestics follows husband and wife Mark (played by Tyler Hoechlin) and Nina (played by Kate Bosworth) as they navigate a dangerous and lawless world where gangs rule the land. After a catastrophic event known as "The Happening" has decimated society, the couple decides to make a perilous journey across the mid-western landscape to reach Nina's family in Milwaukee.
Along the way, they encounter various brutal and lawless factions, each with their own twisted rules and customs. They must navigate through hostile territory, facing off against violent gangs such as The Plowboys, The Nailers, and The Gamblers, all of whom are intent on controlling the post-apocalyptic world.
As they travel, Mark and Nina must rely on their wits, survival skills, and love for each other to endure the horrors they encounter. Along the way, they make allies and enemies, all while trying to stay one step ahead of the ruthless gangs that roam the land.
The Domestics is a tense and thrilling journey of survival, love, and determination in a world where danger lurks around every corner and trust is a rare commodity. As Mark and Nina fight to return home, they must confront their own inner demons and the harsh reality of a world forever changed by apocalypse.