The Book of Eli follows the journey of Eli (Denzel Washington), a man walking alone on a post-apocalyptic Earth, 30 years after a catastrophic nuclear war. Eli is a deeply religious man who believes that he has been chosen by a higher power to protect a sacred book - a book that holds the secrets to saving humankind.
As Eli travels west, he faces numerous dangers, including gangs of violent scavengers who are desperate for valuable resources such as water and food. But Eli is no ordinary man - he is a skilled fighter and marksman, and he is able to fend off most attackers with ease.
Along the way, Eli meets a young woman named Solara (Mila Kunis), who begs Eli to take her under his wing and teach her how to survive. Despite his initial reluctance, Eli eventually agrees to take Solara with him on his journey.
Meanwhile, Eli is pursued by a ruthless man named Carnegie (Gary Oldman), who is also after the sacred book. Carnegie rules a small town and wants to use the book's power to gain control over more people and resources.
In the climactic showdown, Eli faces off against Carnegie and his men, using all his skills to protect the book and prevent its secrets from falling into the wrong hands. Ultimately, Eli is able to deliver the book to a safe location where it can be used to rebuild civilization and restore hope to humanity.