Spunk's Not Dead follows six different characters whose lives are affected by a new drug known as "Spunk." The drug, which is a white powder, has taken over the streets and causes its users to become highly aggressive and violent.
The first story follows a struggling actor who becomes addicted to Spunk after being introduced to it by his dealer. He must navigate his addiction while trying to keep his career afloat.
The second story focuses on a preppy college student who becomes a Spunk addict and begins to spiral out of control. She eventually ends up homeless and in dire need of help.
The third story follows a police detective who becomes obsessed with stopping the spread of Spunk. He goes on a dangerous mission to take down the dealers and suppliers.
In the fourth story, a single mother turns to selling Spunk to make ends meet. She soon finds herself in over her head and must find a way to get out before it's too late.
The fifth story follows a group of teenagers who experiment with Spunk and quickly become hooked. They must try to hide their addiction from their parents and teachers while dealing with the consequences of their choices.
The final story showcases a couple who have been happily married for years until the husband becomes addicted to Spunk. His addiction takes a toll on their relationship, and his wife must decide whether to stay and help him or leave him for good.
As the movie progresses, the devastating effects of Spunk become apparent. The characters' lives become intertwined as they try to navigate their addiction and the dangerous world of drug use.