Spider-Man 3 features Tobey Maguire reprising his role as Peter Parker/Spider-Man, Kirsten Dunst returning as Mary Jane Watson, and James Franco as Harry Osborn. The film introduces several new villains, including Flint Marko/Sandman (played by Thomas Haden Church) and Eddie Brock/Venom (played by Topher Grace).
The plot revolves around Peter Parker's struggle with the alien symbiote that enhances his powers but also corrupts his personality. As he battles Sandman and Venom, he becomes increasingly aggressive and egotistical, causing rifts in his personal relationships. Meanwhile, Mary Jane faces her own challenges as her career as a Broadway actress flounders.
The film also explores the complicated friendship between Peter and Harry, who blames Spider-Man for his father's death. When Harry discovers Peter's secret identity, he becomes the new Green Goblin and attacks him. The climax of the movie sees Peter donning a black suit and embracing his darker side, before eventually defeating Sandman and Venom.
While the movie was a commercial success, it received mixed reviews from critics and is often considered the weakest installment in the original Spider-Man trilogy. However, it remains a popular entry in the superhero movie genre and is notable for its ambitious storyline and memorable set pieces.