The three friends, Dave, Doofer, and Adam, are falsely accused of stealing the money by a rival frat house. As a result, they are kicked out of their fraternity and are forced to dress up as women and move into a neighboring sorority house.
As the trio tries to clear their names and find evidence to prove their innocence, they encounter various challenges and mishaps, including dealing with curious sorority sisters and trying to maintain their disguised identities.
The three friends also begin to learn the importance of sisterhood and solidarity as they become more entrenched in sorority life. However, their efforts to clear their names are complicated by a budding romance between Adam and one of the sorority sisters, which threatens to unravel their plans.
In the end, the trio is able to clear their names and prove their innocence, and they realize the importance of loyalty and friendship. The movie ends with them attending the cocktail cruise as their true selves, with their futures secured and their bond as friends stronger than ever.