Mesrine: Killer Instinct is a crime thriller film which tells the story of Jacques Mesrine, one of the most notorious criminals in French history. The movie is based on the real-life experiences of the protagonist, who was a charismatic and flamboyant figure in the Parisian underworld during the 1960s and 70s.

After returning from the army, Mesrine becomes disillusioned with his mundane life and stumbles into a life of crime. He is quickly drawn into the seedy underworld of Paris and begins working for Guido, a veteran criminal who takes him under his wing. Guido introduces Mesrine to the pleasures of fast money, women, and violence, and shows him how to outsmart the law.

Mesrine quickly rises through the criminal ranks and becomes a notorious figure in Parisian society. He becomes known for his daring bank robberies, audacious prison escapes, and his ability to evade the police. Despite his criminal activities, Mesrine remains a highly charismatic and likable character, who is loved by the public, especially the media who dubbed him "Public enemy number one".

The film is directed by Jean-Francois Richet and stars Vincent Cassel as Mesrine. The movie is a two-part series, with the second film Mesrine: Public Enemy Number One, tracing the later years of Mesrine's criminal career and his ultimate downfall. Mesrine: Killer Instinct is a thrilling and gripping movie, which vividly captures the story of a notorious criminal mastermind and his rise to infamy.

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