As the mutated ape, dubbed "Mega Ape" by the media, rampages through the streets of Hollywood, chaos ensues. The animal has developed superhuman strength and intelligence, making it almost impossible for authorities to contain it.
Meanwhile, a group of scientists who had been working on the genetics project at the facility are desperately trying to track down Mega Ape before it causes any more damage. They fear that, if the animal is not stopped soon, it could result in widespread destruction.
As the city spirals out of control, a young actress named Sarah (played by Emma Stone) finds herself caught up in the chaos. Sarah is filming a new movie on location when Mega Ape attacks, forcing her and her crew to flee for their lives.
In the midst of the chaos, Sarah meets a rugged survivalist named Jackson (played by Dwayne Johnson), who agrees to help her survive the outbreak. Together, they lead a group of survivors through the chaos, dodging Mega Ape's attacks and fighting for their lives.
As the death toll rises and the city is left in ruins, Sarah and Jackson begin to realize that Mega Ape may not be acting of its own accord. It soon becomes clear that someone has harnessed the animal's superhuman abilities for their own gain, and they must now work together to track down this mysterious figure and defeat them before it's too late.
The movie builds to a thrilling climax as Sarah, Jackson, and their allies confront Mega Ape's captors, leading to an epic showdown that will determine the fate of the city and the lives of all involved. Will they be able to stop the creature before it's too late, or is Hollywood doomed to be forever changed by Mega Ape's unstoppable wrath?