Mags and Julie Go on a Road Trip follows two best friends, Maggie (Elaine Partnow) and Julie (Samantha Kern), who embark on a wild road trip across the United States in a beat-up old car. Maggie is a free-spirited, adventurous woman who always seems to be getting herself into crazy situations, while Julie is a more reserved, practical person who tries to keep Maggie grounded.
As they travel from state to state, the two women encounter a variety of colorful characters, including a group of quirky hitchhikers, a handsome cowboy, and a pair of bickering elderly sisters. Along the way, they discover new things about each other and themselves, and ultimately learn the true meaning of friendship.
The film is a comedic and heartwarming tale of female friendship that explores themes of aging, family, and the pursuit of happiness. It is a celebration of the bond between women and the power of adventure, laughter, and love.