The woman's name is Liza, and she is played by Zoe Lister-Jones. She is determined to make it to her friend's party on the last day on Earth, despite the chaos and destruction happening all around her in Los Angeles.
Along her journey, Liza meets a variety of characters, including a drug dealer (played by Fred Armisen), a pregnant woman (played by Whitney Cummings), a self-help guru (played by Nick Kroll), and a screenwriter (played by Charlie Day). Each encounter leads Liza to reflect on her life and relationships, as well as the impending end of the world.
As Liza navigates through the city, she witnesses riots, looting, and mass panic. However, she also encounters moments of unexpected kindness and connection with strangers. Through it all, Liza remains focused on reaching her destination, even as the clock ticks down to the end of the world.
The film is a mixture of comedy and drama, with poignant moments that explore themes of mortality, friendship, and love. The ending is left ambiguous, as Liza finally arrives at the party and the screen fades to black, leaving the audience to wonder what happens next.