The documentary follows Joe Cross as he embarks on a journey to reclaim his health and vitality by adopting a 60-day juice fast. The film also features the stories of other individuals who joined Joe on his journey, including Phil Staples, who was also overweight and suffering from various health issues.
Throughout the course of the film, Joe and Phil experience significant improvements in their physical and emotional health, as well as significant weight loss. The film also highlights the benefits of juicing and plant-based diets, and explores the challenges and obstacles that can arise when trying to make significant lifestyle changes.
Ultimately, Fat, Sick & Nearly Dead serves as a powerful testament to the power of taking control of one's health and well-being, and the transformative effects that can result from doing so.