Do Revenge follows the story of Madison, a former queen bee at a prestigious private high school who was dethroned by her former best friend, Skylar. Madison, who is known for her ruthless tactics, hatches a plan for revenge but needs someone who can do her dirty work for her.
Enter Sam, a new student at the school who is unassuming and does not have any social standing or prior knowledge of the school's social politics. Madison approaches Sam with a proposition: she will teach her how to navigate the complexities of the high school social scene, and in return, Sam will help her exact revenge on Skylar and her clique.
Sam reluctantly agrees to the deal, and the two girls begin working together to take down their enemies. As they get closer to their end goal, however, they begin to question each other's intentions and realize that they have more in common than they initially thought.
Amidst the drama and the high-stakes game of revenge, the two girls realize that they have found an unlikely friendship in each other. With the help of their newfound bond, they are able to take down their enemies and emerge victorious in the end.