Cassandro follows the life of Saúl Armendáriz as he navigates his way through the world of professional wrestling in Mexico. As an openly gay wrestler, he is met with constant discrimination and harassment from both his fellow wrestlers and fans alike. However, he refuses to let their bigotry stop him from pursuing his passion and becomes one of the most popular and innovative wrestlers in Lucha Libre.
Along the way, Cassandro faces numerous personal struggles, including addiction and family problems. He also grapples with the complex intersection of his sexuality and masculinity, as well as the toll that a career in wrestling takes on his body.
Despite the challenges he faces, Cassandro becomes a beloved icon in the Lucha Libre community, known for his flamboyant costumes, makeup, and dramatic flair in the ring. Through his perseverance and determination, he challenges the hyper-masculine norms of the wrestling world and inspires countless others to follow in his footsteps.
The film also delves into the larger cultural significance of Cassandro's legacy, as he becomes an unlikely symbol of LGBTQ+ pride and acceptance in Mexico and beyond.