And God Said to Cain is a 1970 Italian-German spaghetti western film directed by Antonio Margheriti. The movie follows the story of a man named Gary Hamilton who is wrongly accused of a crime and sentenced to ten years in prison. After serving his sentence, he is released and sets out to seek revenge on the people who framed him.

Hamilton starts his journey by searching for the man who actually committed the crime. Along the way, he encounters several obstacles, including a group of bandits who try to kill him and a woman named Maria who tries to help him. Hamilton eventually discovers that the man responsible for the crime is a powerful landowner named Barrett. He also learns that Barrett was helped by Hamilton's former best friend, Richard.

Hamilton tracks down Barrett and Richard and confronts them. In a final showdown, Hamilton kills Richard and wounds Barrett. He then spares Barrett's life and allows him to live, hoping that he will spend the rest of his days regretting what he has done.

The film is notable for its atmospheric visuals, moody music score, and gritty violence. The movie's themes of revenge and justice echo throughout the film. And God Said to Cain is widely regarded as one of the best spaghetti westerns of all time, noted for its strong performances, stylish direction, and compelling storyline.

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